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Matt Will

Matt Will, Tutor

Assistant Professor
340E Life Sciences Center
573-884-2570
willm@missouri.edu
Behavioral Neuroscience

Research area(s):

The focus of my laboratory is to apply methods of behavioral neuroscience towards the study of drug addiction and obesity. Using an animal model, we attempt to reveal the neural substrates that underlie the reinforcement process that contributes to the intake of addictive drugs and natural rewards, such as food. We also investigate the phenomenon by which exposure to environmental stress can augment the reinforcing value of both drugs of abuse and food. Our research addresses these concerns and questions through an integrative approach of behavioral, pharmacological, and molecular biological techniques.

Publications:

KE Parker, JG McCall, MJ Will. (2010). "Basolateral amygdala opioids contribute to increased high-fat intake following intra-accumbens opioid administration, but not following 24-hr food deprivation." Pharmacology, Biochemistry, and Behavior (in press).

CE Pritchett, AL Pardee, SR McGuirk, MJ Will. (2010) "The role of nucleus accumbens adenosine-opioid interaction in mediating palatable food intake." Brain Research. Jan; 1306: 85-92.

MJ Will, CE Pritchett, KE Parker, AM Sawani, H Ma, AY Lai. (2009) "Behavioral characterization of amygdala involvement in mediating intra-accumbens opioid-driven feeding behavior." Behavioral Neuroscience. Vol. 123, No. 4, 781-793.

Fountain ED, Mao J, Whyte JJ, Mueller KE, Ellersieck MR, Will MJ, Roberts RM, Macdonald R, Rosenfeld CS. (2008). "Effects of diets enriched in omega-3 and omega-6 polyunsaturated fatty acids on offspring sex-ratio and maternal behavior in mice." Biol Reprod. Feb; 78(2):211-7.

DK Miller, JR Lever, KR Rodvelt, JA Baskett, MJ Will, GR Kracke. (2007). "Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists." Drug Alcohol Depend. Jul 10;89(2-3):282-91.

MJ Will, W Van der Heyden, AE Kelley. (2007). "Striatal opioid peptide gene expression differentially tracks short-term satiety but does not vary with negative energy balance, in a manner opposite to hypothalamic NPY." Am J Physiol Regul Integr Comp Physiol. Jan 292 (1): R217-26.

2009 Curators of the University of Missouri. DMCA and other copyright information. An equal opportunity/affirmative action institution.

For more information about the program, e-mail alcoholstudies@missouri.edu.