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Psychological Sciences at MU

Kathleen Bucholz, Tutor

Professor, Dept. of Psychiatry, Washington University School of Medicine

Research area(s):

Dr. Bucholz is a psychiatric genetic epidemiologist who has conducted research on psychiatric disorders, including substance use disorders, in community and clinical samples for over 20 years. Her interests are in the development and course of SUDs and comorbid phenotypes, including the influence that genes and environment play in this unfolding, and in the classification of SUDs.


Agrawal, A. A., Lynskey, M. T., Todorov, A. A., Schrage, A. A., Littlefield, A. K.*, Grant, J. D., Zhu, Q., Nelson, E. C., Madden, P. A. F., Bucholz, K. K., Sher, K. J. & Heath, A. C. (2011). A candidate gene association study of alcohol consumption in young women. Journal of Studies on Alcohol and Drugs, 35, 550-558.  PMID: 21143251.

Agrawal, A., Grant, J. D., Littlefield, A. K.*, Waldron, M., Pergadia, M. L., Lynskey, M. T., Madden, P. A. F. , Todorov, A., Trull, T., Bucholz, K. K., Todd, R. D., Sher, K. J. & Heath,  A. C. (2009). Developing a quantitative measure of alcohol consumption for genomic studies on prospective cohorts. Journal of Studies on Alcohol and Drugs, 70, 157-168. PMID: 19261227  PMCID: PMC2653602.

Duncan, A. E., Neuman, R. J., Kramer, J. R., Kuperman, S., Hesselbrock, V. M., & Bucholz, K. K. (2006). Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women. Drug and Alcohol Dependence, 84, 122-132. PMID: 16455211.

Duncan, A. E., Sartor, C., Scherrer, J. F., Grant, J. D., Heath, A. C., Nelson, E. C., Jacob, T., & Bucholz, K. K. (2008). The association between cannabis abuse and dependence and childhood physical and sexual abuse: Evidence from an offspring of twins design. Addiction, 103, 990-997. PMID: 18482422  PMCID: PMC2653098.

Edens, E. L., Glowinski, A. L., Grazier, K. L., & Bucholz, K. K (2007). The 14-year course of alcoholism in a community sample: Do men and women differ? Drug and Alcohol Dependence, 93, 1-11. PMID: 17935914; PMCID: PMC2324065.

Edens, E., Glowinski, A., Pergadia, M., Glowinski, A., Lessov-Schlaggar, C., & Bucholz, K. K. (2010). Nicotine addiction in light smoking African American mothers. Journal of Addiction Medicine, 4, 55-60. PMID: 20582148  PMCID: PMC2889673.

Jackson, K. M., Sher, K. J., Wood, P. K., & Bucholz, K. K. (2003). Alcohol and tobacco use disorders in a general population: Short term and long term associations from the St. Louis ECA Study. Drug and Alcohol Dependence, 71, 239-253. PMID: 12957342.

Jahng, S., Trull, T. J., Wood, P. K., Tragesser, S. L.*, Tomko, R.*, Grant, J. D., Bucholz, K. K., & Sher, K. J. (in press). Distinguishing general and specific personality disorder features and implications for substance dependence comorbidity. Journal of Abnormal Psychology.  

Kristjansson, S. D., Agrawal, A., Littlefield, A. K.*, Pergadia, M. L., Lessov-Schlaggar, C. N., Sartor, C. E., Bucholz, K. K., Madden, P. A., Cooper, M. L., Sher, K. J., & Heath, A. C. (2011). Drinking motives in female smokers: factor structure, alcohol dependence, and genetic influences. Alcoholism: Clinical and Experimental Research, 35, 345-354. PMID: 21083669.

Littlefield, A. K.*, Agrawal, A., Ellingson, J. M.*, Kristjansson, S., Madden, P. A. F., Bucholz, K. K., Slutske, W. S., Heath, A. C., & Sher, K. J. (in press). Does variance in drinking motives explain the genetic overlap between personality and alcohol use disorder symptoms? A twin study of young women. Alcoholism: Clinical and Experimental Research.

McCutcheon, V. V., Agrawal, A., Heath, A. C., Edenberg, H. J., Hesselbrock, V. M., Schuckit, M.A ., Kramer, J. R., & Bucholz, K. K. (in press). Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol. Alcoholism: Clinical and Experimental Research.

McCutcheon, V. V., Heath, A. C., Edenberg, H. J., Grucza, R. A., Hesselbrock, V. M., Kramer, J. R., Bierut, L. J., & Bucholz, K. K. (2009). Alcohol criteria endorsement and psychiatric and drug use disorders among DUI offenders: Greater severity among women and multiple offenders. Addictive Behaviors, 34, 432-439. PMID: 19167170  PMCID: PMC2855219.

Sacco, P., Bucholz, K. K., & Spitznagel, E. L. (2009). Alcohol use among older adults in the National Epidemiologic Survey on Alcohol and Related Conditions: A latent class analysis. Journal for Studies on Alcohol and Drugs, 70, 829-838. PMID: 19895759  PMCID: PMC2776115.

Scherrer, J. F., Grant, J. D., Duncan, A. E., Pan, H., Waterman, B., Jacob, T., Haber, J. R., True, W. R., Heath, A. C., & Bucholz, K. K. (2008). Measured environmental contributions to cannabis abuse/dependence in an offspring of twins design. Addictive Behaviors, 33, 1255-1266. PMID:18583065  PMCID: PMC2633646.

Scherrer, J. F., Grant, J. D., Duncan, A. E., Sartor, C. E., Haber, J. R., Jacob, T., & Bucholz, K. K. Subjective effects to cannabis are associated with use, abuse and dependence after adjusting for genetic and environmental influence. Drug and Alcohol Dependence, 105, 76-82. PMID: 19628344.

2009 Curators of the University of Missouri. DMCA and other copyright information. An equal opportunity/affirmative action institution.

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